Areas of Research
Academic interests
The Kang Laboratory is studying energy metabolism in human disease to answer the following questions:
What are the metabolic changes in endocrine disorders, including diabetes, and diabetic complications?
What is the mechanisms of metabolic dysfunction in refractory cancer related inflammation ?
How can we translate our understanding of energy metabolism into novel therapeutics in human disease?
Our research projects include:
Multi-organ communications in cancer cachexia and metabolic disease
Metabolic Stress or Mitochondrial stress induced response and Mitokine's role in chronic inflammation
Multi-omics data based new integrated signaling pathways in metabolic disease
Our research approach
The Kang Laboratory uses multi-omics data from human samples from patients with metabolic disorder or cancer. Functional studies, such as mouse models, to enhance our understanding of the molecular mechanisms that govern the cellular pathways of cancer metabolism and Cancer cachexia. Our goal is to then translate our research discoveries into the clinic through novel therapeutics targeting in these metabolic pathways.